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URB-597

(10g)

$200
 

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$600
 

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Full Chemical Name:                          URB-597
Systematic IUPAC Name                 
[3-(3-Carbamoylphenyl)phenyl] N-cyclohexylcarbamate
CAS Number                                          
546141-08-6
ChemSpider Number                       
1156960
Molecular Formula                            C20H22N2O3
Molecular Mass                                   
338.41 g·mol−1



What is Ketamine HCL Crystal Powder?
The enzyme fatty acid amide hydrolase (FAAH) is widely expressed in brain and other tissues, and is capable of hydrolyzing anandamide (AEA) and other simple esters and amides with long unsaturated acyl chains.1 The enzyme fatty acid amide hydrolase (FAAH) is widely expressed in brain and other tissues, and is capable of hydrolyzing anandamide (AEA) and other simple esters and amides with long unsaturated acyl chains.1 URB597 was recently synthesized and reported to be a potent and selective inhibitor of FAAH.2 URB597 inhibits FAAH with an IC50 of 4.6 nM in brain membranes and 0.5 nM in intact neurons. It has been demonstrated in FAAH(-/-) mice that marked depression of FAAH activity results in reduced sensation of pain and enhanced endocannabinoid signalling.3 URB597 exhibits both anti-nociceptive and anxiolytic effects in vivo without evoking other symptoms associated with cannabinoid-like compounds. Thus, URB597 may serve as a lead compound for the development of new analgesic and anxiolytic drugs.
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